Publications

Selected Publications. Full information on PubMed.

1. Chekuri A, Zientara-Rytter K, Soto-Hermida A, Borooah S, Voronchikhina M, Biswas P, Kumar V, Goodsell D, Hayward C, Shaw P, Stanton C, Garland D, Subramani S, Ayyagari R. Late-onset retinal degeneration pathology due to mutations in CTRP5 is mediated through HTRA1. Aging Cell. 2019 Dec; 18(6):e13011. PMID: 31385385.

View in: PubMed  

2. Amador-Patarroyo MJ, Lin T, Meshi A, Dans KC, Chen K, Borooah S, Molano-Gonzalez N, Díaz-Rojas JA, Freeman WR. Identifying the factors for improving quality of oral fluorescein angiography. Br J Ophthalmol. 2019 Jul 04. PMID: 31272951.

View in: PubMed 

3. Smith EN, D’Antonio-Chronowska A, Greenwald WW, Borja V, Aguiar LR, Pogue R, Matsui H, Benaglio P, Borooah S, D’Antonio M, Ayyagari R, Frazer KA. Human iPSC-Derived Retinal Pigment Epithelium: A Model System for Prioritizing and Functionally Characterizing Causal Variants at AMD Risk Loci. Stem Cell Reports. 2019 06 11; 12(6):1342-1353. PMID: 31080113.

View in: PubMed 

4. Chekuri A, Sahu B, Chavali VRM, Voronchikhina M, Soto-Hermida A, Suk JJ, Alapati AN, Bartsch DU, Ayala-Ramirez R, Zenteno JC, Dinculescu A, Jablonski MM, Borooah S, Ayyagari R. Long-Term Effects of Gene Therapy in a Novel Mouse Model of Human MFRP-Associated Retinopathy. Hum Gene Ther. 2019 05; 30(5):632-650. PMID: 30499344.

View in: PubMed

5. Borooah S, Stanton CM, Marsh J, Carss KJ, Waseem N, Biswas P, Agorogiannis G, Raymond L, Arno G, Webster AR. Whole genome sequencing reveals novel mutations causing autosomal dominant inherited macular degeneration. Ophthalmic Genet. 2018 12; 39(6):763-770. PMID: 30451557.

View in: PubMed

6. Chekuri A, Guru AA, Biswas P, Branham K, Borooah S, Soto-Hermida A, Hicks M, Khan NW, Matsui H, Alapati A, Raghavendra PB, Roosing S, Sarangapani S, Mathavan S, Telenti A, Heckenlively JR, Riazuddin SA, Frazer KA, Sieving PA, Ayyagari R. IFT88 mutations identified in individuals with non-syndromic recessive retinal degeneration result in abnormal ciliogenesis. Hum Genet. 2018 Jul; 137(6-7):447-458. PMID: 29978320.

View in: PubMed 

7. Mehat MS, Sundaram V, Ripamonti C, Robson AG, Smith AJ, Borooah S, Robinson M, Rosenthal AN, Innes W, Weleber RG, Lee RWJ, Crossland M, Rubin GS, Dhillon B, Steel DHW, Anglade E, Lanza RP, Ali RR, Michaelides M, Bainbridge JWB. Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in Macular Degeneration. Ophthalmology. 2018 11; 125(11):1765-1775. PMID: 29884405.

View in: PubMed 

8. Gonzalez-Cordero A, Goh D, Kruczek K, Naeem A, Fernando M, Kleine Holthaus SM, Takaaki M, Blackford SJI, Kloc M, Agundez L, Sampson RD, Borooah S, Ovando-Roche P, Mehat MS, West EL, Smith AJ, Pearson RA, Ali RR. Assessment of AAV Vector Tropisms for Mouse and Human Pluripotent Stem Cell-Derived RPE and Photoreceptor Cells. Hum Gene Ther. 2018 10; 29(10):1124-1139. PMID: 29580100.

View in: PubMed 

9. Elwes F, Borooah S, Aspinall P, Sim PY, Loo CY, Armbrecht AM, Dhillon B, Cackett P. Clinical outcomes of switching to aflibercept using a pro re nata treatment regimen in patients with neovascular age-related macular degeneration who incompletely responded to ranibizumab. BMC Ophthalmol. 2018 Jan 30; 18(1):20. PMID: 29378528.

View in: PubMed

10. Selvaraj BT, Livesey MR, Zhao C, Gregory JM, James OT, Cleary EM, Chouhan AK, Gane AB, Perkins EM, Dando O, Lillico SG, Lee YB, Nishimura AL, Poreci U, Thankamony S, Pray M, Vasistha NA, Magnani D, Borooah S, Burr K, Story D, McCampbell A, Shaw CE, Kind PC, Aitman TJ, Whitelaw CBA, Wilmut I, Smith C, Miles GB, Hardingham GE, Wyllie DJA, Chandran S. C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity. Nat Commun. 2018 01 24; 9(1):347. PMID: 29367641.

View in: PubMed 

11. Sim PY, Gajree S, Dhillon B, Borooah S. Investigation of time to first presentation and extrahospital factors in the treatment of neovascular age-related macular degeneration: a retrospective cross-sectional study. BMJ Open. 2017 Dec 10; 7(12):e017771. PMID: 29229653.

View in: PubMed 

12. Sii S, Aspinall P, Borooah S, Dhillon B. Exploring factors predicting changes in patients’ expectations and psychosocial issues during the course of treatment with intravitreal injections for wet age-related macular degeneration. Eye (Lond). 2018 04; 32(4):673-678. PMID: 29219960.

View in: PubMed

13. Stanton CM, Borooah S, Drake C, Marsh JA, Campbell S, Lennon A, Soares DC, Vallabh NA, Sahni J, Cideciyan AV, Dhillon B, Vitart V, Jacobson SG, Wright AF, Hayward C. Novel pathogenic mutations in C1QTNF5 support a dominant negative disease mechanism in late-onset retinal degeneration. Sci Rep. 2017 09 22; 7(1):12147. PMID: 28939808.

View in: PubMed 

14. Teh BL, Megaw R, Borooah S, Dhillon B. Response to the Letter to the Editor-Fresnel Prism Intraocular Lens and Scharioth Macula Lens. Surv Ophthalmol. 2018 Jan – Feb; 63(1):133. PMID: 28818456.

View in: PubMed

15. Papastavrou VT, Borooah S, O’Brien JM, Ray-Chaudhuri N, Dhillon B, Vieira RV, Browning AC. Cataract surgery in patients with late-onset retinal degeneration. J Cataract Refract Surg. 2017 08; 43(8):1036-1043. PMID: 28917403.

View in: PubMed 

16. Gajree S, Borooah S, Dhillon N, Goudie C, Smith C, Aspinall P, Dhillon B. Temporal artery biopsies in south-east Scotland: a five year review. J R Coll Physicians Edinb. 2017 Jun; 47(2):124-128. PMID: 28675180.

View in: PubMed 

17. Gajree S, Borooah S, Dhillon B. Imaging in Diabetic Retinopathy: A Review of Current and Future Techniques. Curr Diabetes Rev. 2017; 13(1):26-34. PMID: 26582042.

View in: PubMed

18. Teh BL, Megaw R, Borooah S, Dhillon B. Optimizing cataract surgery in patients with age-related macular degeneration. Surv Ophthalmol. 2017 May – Jun; 62(3):346-356. PMID: 28012877.

View in: PubMed 

19. Balmforth C, van Bragt JJ, Ruijs T, Cameron JR, Kimmitt R, Moorhouse R, Czopek A, Hu MK, Gallacher PJ, Dear JW, Borooah S, MacIntyre IM, Pearson TM, Willox L, Talwar D, Tafflet M, Roubeix C, Sennlaub F, Chandran S, Dhillon B, Webb DJ, Dhaun N. Chorioretinal thinning in chronic kidney disease links to inflammation and endothelial dysfunction. JCI Insight. 2016 12 08; 1(20):e89173. PMID: 27942587.

View in: PubMed 

20. Andrews J, Borooah S. Endocarditis and monocular blindness. BMJ Case Rep. 2016 Oct 26; 2016. PMID: 27797843.

View in: PubMed 

21. Kontos G, Borooah S, Khan A, Fleck BW, Coupland SE. The epidemiology, clinical characteristics, histopathology and management of juvenile- and adult-onset corneoscleral limbus xanthogranuloma. Graefes Arch Clin Exp Ophthalmol. 2016 Mar; 254(3):413-20. PMID: 26794218.

View in: PubMed

22. Govindasamy G, Barber BE, Ghani SA, William T, Grigg MJ, Borooah S, Dhillon B, Dondorp AM, Yeo TW, Anstey NM, Maude RJ. Retinal Changes in Uncomplicated and Severe Plasmodium knowlesi Malaria. J Infect Dis. 2016 May 01; 213(9):1476-82. PMID: 26671886.

View in: PubMed 

23. Rzechorzek NM, Connick P, Livesey MR, Borooah S, Patani R, Burr K, Story D, Wyllie DJA, Hardingham GE, Chandran S. Hypothermic Preconditioning Reverses Tau Ontogenesis in Human Cortical Neurons and is Mimicked by Protein Phosphatase 2A Inhibition. EBioMedicine. 2016 Jan; 3:141-154. PMID: 26870825.

View in: PubMed 

24. MacCormick IJ, Maude RJ, Beare NA, Borooah S, Glover S, Parry D, Leach S, Molyneux ME, Dhillon B, Lewallen S, Harding SP. Grading fluorescein angiograms in malarial retinopathy. Malar J. 2015 Sep 24; 14:367. PMID: 26403288.

View in: PubMed 

25. Borooah SR. Author’s reply to Gilchrist and Artes. BMJ. 2015 Jul 14; 351:h3747. PMID: 26175268.

View in: PubMed

26. Borooah S, Dhillon A, Dhillon B. Gradual loss of vision in adults. BMJ. 2015 Jun 08; 350:h2093. PMID: 26055964.

View in: PubMed 

27. Borooah S, Jeganathan VS, Ambrecht AM, Oladiwura D, Gavin M, Dhillon B, Cackett P. Long-term visual outcomes of intravitreal ranibizumab treatment for wet age-related macular degeneration and effect on blindness rates in south-east Scotland. Eye (Lond). 2015 Sep; 29(9):1156-61. PMID: 26043706.

View in: PubMed 

28. Gamal W, Borooah S, Smith S, Underwood I, Srsen V, Chandran S, Bagnaninchi PO, Dhillon B. Real-time quantitative monitoring of hiPSC-based model of macular degeneration on Electric Cell-substrate Impedance Sensing microelectrodes. Biosens Bioelectron. 2015 Sep 15; 71:445-455. PMID: 25950942.

View in: PubMed

29. Devlin AC, Burr K, Borooah S, Foster JD, Cleary EM, Geti I, Vallier L, Shaw CE, Chandran S, Miles GB. Human iPSC-derived motoneurons harboring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability. Nat Commun. 2015 Jan 12; 6:5999. PMID: 25580746.

View in: PubMed 

30. Maude RJ, Ahmed BU, Rahman AH, Rahman R, Majumder MI, Menezes DB, Abu Sayeed A, Hughes L, MacGillivray TJ, Borooah S, Dhillon B, Dondorp AM, Faiz MA. Retinal changes in visceral leishmaniasis by retinal photography. BMC Infect Dis. 2014 Sep 30; 14:527. PMID: 25270641.

View in: PubMed 

31. Aspinall PA, Borooah S, Al Alouch C, Roe J, Laude A, Gupta R, Gupta M, Montarzino A, Dhillon B. Gaze and pupil changes during navigation in age-related macular degeneration. Br J Ophthalmol. 2014 Oct; 98(10):1393-7. PMID: 24831715.

View in: PubMed 

32. Prescott G, Sharp P, Goatman K, Scotland G, Fleming A, Philip S, Staff R, Santiago C, Borooah S, Broadbent D, Chong V, Dodson P, Harding S, Leese G, Megaw R, Styles C, Swa K, Wharton H, Olson J. Improving the cost-effectiveness of photographic screening for diabetic macular oedema: a prospective, multi-centre, UK study. Br J Ophthalmol. 2014 Aug; 98(8):1042-9. PMID: 24682180.

View in: PubMed 

33. Maude RR, Hossain MA, Hassan MU, Osbourne S, Sayeed KL, Karim MR, Samad R, Borooah S, Dhillon B, Day NP, Dondorp AM, Maude RJ. Transorbital sonographic evaluation of normal optic nerve sheath diameter in healthy volunteers in Bangladesh. PLoS One. 2013; 8(12):e81013. PMID: 24312515.

View in: PubMed

34. Olson J, Sharp P, Goatman K, Prescott G, Scotland G, Fleming A, Philip S, Santiago C, Borooah S, Broadbent D, Chong V, Dodson P, Harding S, Leese G, Styles C, Swa K, Wharton H. Improving the economic value of photographic screening for optical coherence tomography-detectable macular oedema: a prospective, multicentre, UK study. Health Technol Assess. 2013 Nov; 17(51):1-142. PMID: 24225334.

View in: PubMed

35. Borooah S, Phillips MJ, Bilican B, Wright AF, Wilmut I, Chandran S, Gamm D, Dhillon B. Using human induced pluripotent stem cells to treat retinal disease. Prog Retin Eye Res. 2013 Nov; 37:163-81. PMID: 24104210.

View in: PubMed 

36. Bujarborua D, Borooah S, Dhillon B. Getting serious with retinopathy: approaching an integrated hypothesis for central serous chorioretinopathy. Med Hypotheses. 2013 Aug; 81(2):268-73. PMID: 23669373.

View in: PubMed

37. Tiong T, Borooah S, Msosa J, Dean W, Smith C, Kambewa E, Kiire C, Zondervan M, Aspinall P, Dhillon B. Clinicopathological review of ocular surface squamous neoplasia in Malawi. Br J Ophthalmol. 2013 Aug; 97(8):961-4. PMID: 23613511.

View in: PubMed 

38. Borooah S, Grant B, Blaikie A, Styles C, Sutherland S, Forrest G, Curry P, Legg J, Walker A, Sanders R. Using electronic referral with digital imaging between primary and secondary ophthalmic services: a long term perspective analysis of regional service redesign. Eye (Lond). 2013 Mar; 27(3):392-7. PMID: 23258310.

View in: PubMed

39. Mitry D, Awan MA, Borooah S, Syrogiannis A, Lim-Fat C, Campbell H, Wright AF, Fleck BW, Charteris DG, Yorston D, Singh J. Long-term visual acuity and the duration of macular detachment: findings from a prospective population-based study. Br J Ophthalmol. 2013 Feb; 97(2):149-52. PMID: 23159447.

View in: PubMed 

40. Mitry D, Awan MA, Borooah S, Siddiqui MA, Brogan K, Fleck BW, Wright A, Campbell H, Singh J, Charteris DG, Yorston D. Surgical outcome and risk stratification for primary retinal detachment repair: results from the Scottish Retinal Detachment study. Br J Ophthalmol. 2012 May; 96(5):730-4. PMID: 22257789.

View in: PubMed

41. Borooah S, Collins C, Wright A, Dhillon B. Republished review. [corrected] Late-onset retinal macular degeneration: clinical insights into an inherited retinal degeneration. Postgrad Med J. 2009 Sep; 85(1007):495-500. PMID: 19734518.

View in: PubMed

42. Borooah S, Collins C, Wright A, Dhillon B. Late-onset retinal macular degeneration: clinical insights into an inherited retinal degeneration. Br J Ophthalmol. 2009 Mar; 93(3):284-9. PMID: 19098033.

View in: PubMed

43. Borooah S, Chadha V, Sutherland S. A case of permanent retinal disturbance postpartum following administration of ergometrine. Can J Ophthalmol. 2008 Oct; 43(5):607-8. PMID: 18982049.

View in: PubMed

44. Mitry D, Schmoll C, Hegde V, Borooah S, Singh J, Bennett H. Use of pegaptanib in the treatment of vitreous hemorrhage in idiopathic retinal vasculitis. Eye (Lond). 2008 Nov; 22(11):1449-50. PMID: 18704126.

View in: PubMed

45. Chadha V, Borooah S. Variations in intake of tamsulosin. J Cataract Refract Surg. 2007 Mar; 33(3):362-3. PMID: 17321374.

View in: PubMed

46. Chadha V, Borooah S, Tey A, Styles C, Singh J. Floppy iris behavior during cataract surgery: associations and variations. Br J Ophthalmol. 2007 Jan; 91(1):40-2. PMID: 16943229.

View in: PubMed